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Choline Bitartrate with Nootropics: Top 4 Stacks

Many people know choline bitartrate as the natural Nootropic. As an essential nutrient, you really just can’t get enough choline.  It has a vital role in memory and cognition.[1]

While most people get enough choline in their diets to avoid health issues from choline deficiency, most do not get enough choline to enjoy the great effects it offers. Taking upwards of 500 mg – 1000 mg of choline daily, you start to feel the potent Nootropic effects of this compound.

Man holding brain - Choline Bitartrate is a natural nootropic Choline is the ultimate natural Nootropic!

1.    Choline Bitartrate with Noopept

People often talk about Noopept as the world’s strongest Nootropic substance. It is a Russian designed compound that improves your blood circulation, as well as increasing mental capacity and memory.[2]

The great thing about using choline bitartrate with Noopept is that choline is the ultimate natural Nootropic, while Noopept offers more of a technologically advanced cognitive boost. It’s the ultimate Nootropic fusion of ancient and modern.

Best of all, choline is an incredibly safe supplement, found in small quantities in almost all food products. Theoretically, and according to many user reviews, combining Noopept and Choline should not result in any negative side effects, although we should mention that this hasn’t been studied yet.


2.   Phenibut and Choline Bitartrate

Phenibut is one of the most sought-after Nootropics on Earth! Like Noopept, Phenibut is a Russian designed compound, built for Russian astronautics expeditions. The key benefit of Phenibut is that it is able to reduce social anxiety and anxiety without reducing your ability to function.[3]

Most substances taken for social anxiety – including alcohol, reduce your motor functions. Phenibut is different. At regular doses, this Nootropic leaves you feeling clear-headed and sociable. This is what makes using Choline Bitartrate with Phenibut such a great Nootropic stack.

Choline bitartrate with phenibut Liftmode Phenibut: 99.5%+ purity

However, phenibut does have its drawbacks. Irresponsible use can result in a tolerance building up, and some people find it addictive. It’s important to note that phenibut isn’t used for a ‘high’. It is, however, a great substance to aid in improving symptoms of anxiety and for promoting healthy sleep.

Choline and phenibut is a great stack to improve your cognition, memory and reduce anxiety. The powerful effects of phenibut combined with the natural Nootropic effects of choline make taking choline with Phenibut a great Nootropic stack!


3.    Choline Bitartrate with Caffeine

Caffeine is the fuel of modern society. Together with alcohol and nicotine, caffeine is the most widely consumed psychoactive substance on this planet. And for good reason.

caffeine - cup overflowing Choline bitartrate with caffeine is a great Nootropic stack!

Caffeine is a powerful stimulant. It increases your energy, physical endurance, mental focus, and cognition. However, you can also get addicted to caffeine and it needs to be used in moderation. Many people suffer from caffeine overdoses around the world each year.[4]

That being said, caffeine used with choline provides a powerful energizing Nootropic stack. Choline is a natural and safe Nootropic that improves both your cognitive performance as well as your memory. Caffeine has a similar effect, as well as providing a powerful energy boost. When you use these two substances together you get the ultimate in mental clarity and focus!


4.    Inositol and Choline Bitartrate

Choline Bitartrate with Inositol is our final great Nootropic stack. Inositol is also an essential nutrient, and it’s important in a number of your biochemical pathways. Inositol is especially important in helping your body to metabolize glucose (sugar). [5]

One of the best things about Inositol is its ability to help with the symptoms of PCOS, a disorder that affects roughly 15% of women around the world. Inositol improves your insulin sensitivity, helping with PCOS and diabetics. It also has a number of secondary health benefits.

Combining inositol and choline is a great health stack!



In conclusion, you can use choline bitartrate as a versatile Nootropic, in combination with a number of substances. We’ve listed the top four Choline stacks, but you can actually use choline with many other great substances, and enjoy some wonderful mental and health benefits.

Liftmode choline, 5 grams Liftmode Choline, 99%+ purity

Our favorite of the four would have to be a tie between Choline Bitartrate with Phenibut and Choline Bitartrate with Caffeine. We feel that these two stacks offer the most that you can get from combining two great substances.




[1] Choline: needed for normal development of memory, SH Zeisel, J Am Coll Nutr. 2000 Oct;19(5 Suppl):528S-531S, available from http://www.ncbi.nlm.nih.gov/pubmed/11023003

[2] Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation, RU Ostrovskaya et al., J Biomed Sci. 2014 Aug 6;21:74. doi: 10.1186, available from http://www.ncbi.nlm.nih.gov/pubmed/25096780

[3] Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug, Lapin I, CNS Drug Rev. 2001 Winter;7(4):471-81, available from http://www.ncbi.nlm.nih.gov/pubmed/11830761

[4] Caffeine, Examine.com, available from https://examine.com/supplements/caffeine/

[5] Inositol: history of an effective therapy for Polycystic Ovary Syndrome, M Bizzarri and G Carlomagno, Eur Rev Med Pharmacol Sci. 2014 Jul;18(13):1896-903, available from http://www.ncbi.nlm.nih.gov/pubmed/25010620