Honokiol

Buy Our Honokiol Extract Supplement

 

Honokiol is a polyphenol isolated from the bark of Magnolia officinalis plant and is traditionally used in Eastern herbal remedies for its calming and neuroprotective properties. It has the chemical formula C18H18O2 and a molecular weight of 266.33 g/mol.

 

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Honokiol Extract Benefits and Uses

 

Chemically, Honokiol is one of the active components of the Magnolia bark extract. It is a structural isomer of magnolol, a neolignan biphenol and a member of the phenolic class of plants. Honokiol has a high bioavailability and is slightly water-soluble.   

 

Honokiol is pleiotropic – meaning it can affect multiple pathways of the body – and is particularly protective of the brain. Honokiol can preserve the activity of mitochondria and sodium-potassium pumps, two processes that are fundamental for the communication of neurons.

 

Anecdotally, the anti-inflammatory and antioxidant properties of Honokiol offer numerous health benefits. These include promoting relaxation and restful sleep as well a healthy digestion.

 

Where to Buy Honokiol Extract Online?

 

LiftMode offers a variety of unit sizes of Honokiol extract including 5-gram (0.18 Oz) and 10-gram (0.35 Oz) units. LiftMode Honokiol is guaranteed 99+% pure.

All our products ship with a certificate of analysis from 3rd-party independent laboratories, and all orders are covered by our 90-days refund/reshipment policy to ensure the highest quality.

 

Shipping restrictions: No shipping restrictions currently apply to this product and we are able to ship internationally. At checkout, the available shipping options for your location will be available.

 

 

Nomenclature:

 

Honokiol extract supplements are also known by a few different names, including:

 

35354-74-6

Houpu

Magnolia officinalis

Kara-koboku 

Indian bark

4-O-methylhonokiol

Chuan Houpu

2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol

5,3-Diallyl-2,4-dihydroxybiphenyl

 

Scientific Consensus:

 

Honokiol is considered a safe and well tolerated herbal supplement with a low toxicity. Doses of 15-30mg/kg of bodyweight per day have been safely administered, without any signs of dependence or side effects.

 

There is not enough data to say whether Honokiol extract is safe for pregnant or breastfeeding women, or if it can be used by children. 

Honokiol has the potential to interact anaesthesia and other medications, and should be avoided before undergoing a surgery.

 

Disclaimer:

 

All dietary supplements have risks. Please ensure that you are familiar with the latest research on effects, side effects, benefits, and uses of a supplement before buying it.

 

Store in a cool, dry place. Keep out of reach of children. If you have any underlying medical conditions or are taking any medication, especially blood thinners or sleeping aids, please consult a medical professional before using this supplement. 

 

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 

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How We Research Our Content

Our content is written using meticulous research methods and claims are backed by links to scientific references, wherever possible. The author and editors of Liftmode's Research Team have strong academic backgrounds in microbiology, physiology, and biochemistry.

Content Updated On: October 13, 2019

 

References:

 

  • National Center for Biotechnology Information. PubChem Database. Honokiol, CID=72303, https://pubchem.ncbi.nlm.nih.gov/compound/Honokiol (accessed on Dec. 7, 2019)

 

  • Chen CM, Liu SH, Lin-Shiau SY. Honokiol, a neuroprotectant against mouse cerebral ischaemia, mediated by preserving Na+, K+-ATPase activity and mitochondrial functions. Basic Clin Pharmacol Toxicol. 2007 Aug;101(2):108-16.PubMed PMID: 17651312.

 

  • Woodbury, A., Yu, S. P., Wei, L., & García, P. (2013). Neuro-modulating effects of honokiol: a review. Frontiers in neurology4, 130. doi:10.3389/fneur.2013.00130

 

  • Sarrica A, Kirika N, Romeo M, Salmona M, Diomede L. Safety and Toxicology of Magnolol and Honokiol. Planta Med. 2018 Nov;84(16):1151-1164. doi:10.1055/a-0642-1966. Epub 2018 Jun 20. Review. PubMed PMID: 29925102.

 

  • Kuribara H, Kishi E, Hattori N, Okada M, Maruyama Y. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol. 2000 Nov;52(11):1425-9. PubMed PMID: 11186252.

 

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