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Agmatine Sulfate

Buy Our Agmatine Sulfate Supplement


Agmatine is a newly understood neurotransmitter that is produced from L-Arginine. It is synthesized in the brain and stored in synaptic vessels for use in receptor signalling pathways. Agmatine has the chemical formula C5H14N4 and a molecular mass of 130.195 g/mol.


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Agmatine Sulfate Reviews


Agmatine Sulfate Benefits and Uses


Agmatine sulphate is an amino acid derivative that has recently been discovered to act as a neurotransmitter. It has been used in research for analgesic and neuroprotective effects. It works primarily as an NMDA receptor antagonist, an alpha-2-adrenergic receptor activator, and a serotonin signal enhancer. It also helps regulate nitric oxide production and may block Ca2+ and K+ channels.


Where to Buy Agmatine Sulfate Online?


LiftMode offers a variety of unit sizes of Agmatine sulphate, including a 100-gram (3.53 Oz), a 200-gram (7.05 Oz) unit and a 500-gram (17.64 Oz) bulk unit. Our Agmatine supplement is guaranteed at a high purity of > 99%.


All our products ship with a certificate of analysis from 3rd-party independent laboratories, and all orders are covered by our 90-days refund/reshipment policy to ensure the highest quality.


Shipping restrictions: No shipping restrictions currently apply to this product and we are able to ship internationally. At checkout, the available shipping options for your location will be available.  




Agmatine Sulfate is known by a number of alternative names, including:




Agmatine Sulfate


Scientific Consensus:


Agmatine is a naturally-occurring chemical found in plant species, animals, and humans. It is made from L-arginine. Agmatine sulfate is considered possibly safe for use by most people at the recommended serving size.


There is still a need for further research to properly understand the significance of its benefits and adverse effects. Some people have reported experiencing diarrhoea, upset stomach, and nausea.  


Warning: There is not enough research about the safety of Agmatine for pregnant and breastfeeding women. Do not use this supplement if you have any underlying medical conditions – especially people with diabetes, or undergoing surgery.




All dietary supplements have risks. Please ensure that you are familiar with the latest research on effects, side effects, benefits, and uses of a supplement before buying it.


Store in a cool, dry place. Keep out of reach of children. If you have any underlying medical conditions or are taking any medication, please consult a medical professional before using this supplement. 


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


buy agmatine sulfate


How We Research Our Content


Our content is written using meticulous research methods and claims are backed by links to scientific references, wherever possible. The author and editors of Liftmode's Research Team have strong academic backgrounds in microbiology, physiology, and biochemistry.

Content Updated On: November 20, 2019




  • Piletz, J. E., Chikkala, D. N., Ernsberger, P. (1995). Comparison of the properties of agmatine and endogenous clonidine-displacing substance at imidazoline and alpha-2 adrenergic receptors. J Pharmacol Exp Ther. 272(2):581-7


  • Wang, C. C., Chio, C. C., Chang, C. H., Kuo, J. R., Chang, C. P. (2010). The beneficial effect of agmatine on brain apoptosis, astrogliosis, and edema after rat transient cerebral ischemia. BMC Pharmacol. 10:11


  • Chang, C. H., Wu, H. T., Cheng, K. C., Lin, H. J., & Cheng, J. T. (2010) Increase of beta-endorphin secretion by agmatine is induced by activation of imidazoline I(2A) receptors in adrenal gland of rats. Neurosci Lett. 2010 Jan 14;468(3):297-9


  • Keynan, O., Mirovsky, Y., Dekel, S., Gilad, V. H., & Gilad, G. M. (2010). Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial. Pain Med. 11(3):356-68. 


  • uiz-Durántez, E., Ruiz-Ortega, J. A., Pineda, J., & Ugedo, L. (2002). Effect of agmatine on locus coeruleus neuron activity: possible involvement of nitric oxide. Br J Pharmacol. 135(5):1152-8