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L-Citrulline DL-Malate 2:1 Powder

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L-Citrulline (2-Amino-5-(carbamoylamino)pentanoic acid) is an alpha amino acid first extracted from watermelons. It is used in the urea cycle and is taken to boost L-arginine levels and, thus, nitric oxide levels. DL-Malate (malic acid) is a key compound for the synthesis of ATP. L-Citrulline DL-Malate 2:1 is composed of 2 L-Citrulline molecules bound to a single Malic Acid molecule.

L-Citrulline DL-Malate 2:1 Benefits and Uses

L-Citrulline DL-Malate 2:1 is a salt made up of two L-Citrulline molecules bound to one Malic acid molecule. L-Citrulline is a naturally occurring α-amino acid which is a key intermediate in mammalian biochemical and metabolic processes, including the urea cycle. Its nomenclature derives from the Latin name of the watermelon fruit (Citrullus vulgaris), in which its concentration exceeds 2mg per gram of fresh watermelon.

L-Citrulline DL-Malate has been found to increase cellular energy production in a synergistic manner. The ratio of two to one is generally preferred by athletes because it optimizes the mass of L-Citrulline delivered per serving.

L-Citrulline supplements are also known by a few different names, including:

  • 2-Amino-5-(carbamoylamino)pentanoic acid
  • Citrulline
  • Watermelon extract
  • L-Citrulina
  • AKG
  • L-Citrulline Malate
  • Citrulline Malate
  • 2:1 Citrulline Malate salt
  • l-critrulline-dl-malate

Scientific Consensus

Supplementing with L-Citrulline DL-Malate 2:1 is likely safe for adults when taken at the recommended serving size. L-Citrulline is a naturally-occurring amino acid, and as such, side effects are rare and uncommon.

Special Warnings

It is very important to talk to your doctor before using this supplement if you are taking any prescription medication. There is not enough research to support the safety of L-Citrulline supplements for pregnant or breastfeeding women. As such, it is recommended to be avoided.

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The statements on this page have not been evaluated by the FDA. The products on this page are not intended to diagnose, treat, cure, or prevent any disease.
July 26, 2021
Zeezer
L-Citrulline DL-Malate 2:1 Powder

Liftmode’s L-Citrulline DL-Malate is top notch. I recently started to add it to my homemade preworkout blend. I get prolonged energy and quality muscle pumps off of moderate dosing.

Serving size is 3000 mg. As a dietary supplement, take 1 serving up to 3 times per day. Please start with the lowest suggested single serving quantity to assess response.

Supplement Facts

Serving size: 3000mg
Servings per container:
Amount per serving: % DV

L-Citrulline

2000 mg
‡

DL-Malate

1000 mg
‡
LiftMode offers a variety of unit sizes of HPLC-tested L-Citrulline DL-Malate 2:1 Powder, including a a 1000g unit, a 200g unit and a 250g unit. Our L-Citrulline DL-Malate 2:1 Powder is of the highest quality.
Store securely in a dry cool location away from direct sunlight. Keep out of reach of children and pets. Do not take this or any other supplement, and instead consult doctor about use, if you are under the age of 18, pregnant or breastfeeding, taking prescription or OTC / nonprescription drugs, or if you have any known or suspected medical conditions. Do not use if product safety seal was damaged or missing upon receipt.
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Scientifically Tailored Ingredients

L-Citrulline is often considered a kind of camouflaged, enhanced efficacy Arginine supplement, due to its rapid conversion into Arginine by the kidneys after consumption.

Unlike most known forms of Arginine, its absorption is not restricted by the Arginine transporter in the intestinal tract, and thus L-Citrulline has significantly reduced (if any) gastrointestinal side effects in comparison to Arginine, even when consumed at large servings.

Arginine, and by extension L-Citrulline, are often supplemented to increase bloodflow through their enhancement of nitric oxide (NO), (which is a small cell signalling molecule that promotes vasodilation and can thus benefit a wide range of human activity). Through this pathway, research indicates that L-Arginine and L-Citrulline may help boost aerobic and anaerobic exercise performance, erection quality, and even healthy growth hormone release.

– Increased NO2 Production
– Boosts Physical Energy
– Improves Exercise Performance

Malic acid, a dicarboxylic acid found in all living organisms, is a key factor in the biosynthesis of ATP (Adenosine Triphosphate, the universal cellular energy carrier molecule), through its role in the citric acid cycle. The combination salt, L-Citrulline DL-Malate, is the most common and bioavailable form of orally available Malic acid.

– Improves Energy Levels
– Enhances L-Citrulline Absorption
– Precursor to ATP

Gonzalez, A. M., & Trexler, E. T. (2020). Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature. Journal of strength and conditioning research, 34(5), 1480–1495. https://doi.org/10.1519/JSC.0000000000003426.

Allerton, T. D., Proctor, D. N., Stephens, J. M., Dugas, T. R., Spielmann, G., & Irving, B. A. (2018). l-Citrulline Supplementation: Impact on Cardiometabolic Health. Nutrients, 10(7), 921. https://doi.org/10.3390/nu10070921.

Gonzales, J. U., Raymond, A., Ashley, J., & Kim, Y. (2017). Does l-citrulline supplementation improve exercise blood flow in older adults?. Experimental physiology, 102(12), 1661–1671. https://doi.org/10.1113/EP086587.

Papadia, C., Osowska, S., Cynober, L., & Forbes, A. (2018). Citrulline in health and disease. Review on human studies. Clinical nutrition (Edinburgh, Scotland), 37(6 Pt A), 1823–1828. https://doi.org/10.1016/j.clnu.2017.10.009.

Farney, T. M., Bliss, M. V., Hearon, C. M., & Salazar, D. A. (2019). The Effect of Citrulline Malate Supplementation on Muscle Fatigue Among Healthy Participants. Journal of strength and conditioning research, 33(9), 2464–2470. https://doi.org/10.1519/JSC.0000000000002356