Dihydromyricetin – also known as DHM or Ampelopsin – is a relatively new supplement that occurs in a number of plant species and is used for metabolic and liver-support benefits. Ampelopsin has the chemical formula C15H12O8 and a molecular weight of 320.253 g/mol.
Dihydromyricetin (DHM) Benefits and Uses
Dihydromyricetin (DHM) is taken by mouth for its antioxidant and general health-supporting benefits. It has long been used in Traditional Chinese Medicine (TCM) for a variety of health-supporting effects. More recently, modern scientific investigations have uncovered several modes of action that corroborate DHM’s support of general health including support of mitochondrial health.
Recent research studies have also revealed several important mechanisms of action relating to DHM’s ability to support normal liver health and tone down some of the unpleasantness surrounding alcohol use.
DHM is known by a number of alternative names including:
- Ampelopsin
- (2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one
- Ampelopsis
- Hovenia dulcis flavonoid extract
- Dihydromyricetin
Scientific Consensus
DHM is likely safe when taken by mouth. It is taken commonly to help ameliorate drawbacks around alcohol use and nourish and uphold normal liver function. As an oral supplement, the recommended serving size of Dihydromyricetin is 400 mg. Take 1-2 servings up to twice per day.
There is still a need for further research into the significance of DHM’s benefits and adverse effects. Nevertheless, Dihydromycetin appears safe for use at the recommended serving size, with only mild side effects very rarely being reported. There is insufficient research to support the use of DHM (Ampelopsin) supplementation during pregnancy and breastfeeding.