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Methylsulfonylmethane (MSM)

Buy Our Methylsulfonylmethane (MSM) Supplement


Methylsulfonylmethane (MSM) is a compound containing a large portion of sulphur, an essential mineral in the human body. MSM is found naturally in plants but is also synthetically produced today as a supplement for its perceived effect in improving pain and inflammatory conditions. MSM  has the chemical formula C2H6O2S and a molecular mass of 94,13 g/mol.


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  1. MSM (Pure OptiMSM® Flakes) - 200 Grams (7.05 Oz)

    MSM (Pure OptiMSM® Flakes) - 200 Grams (7.05 Oz)


    Availability:Only 5 left

    MSM (Methylsulfonylmethane) is a naturally occurring organosulfur compound and, like DMSO, is considered an important sulfur donor. Sulfur is important for connective tissue health, as it is incorporated into cartilage in order to retain water and therefore elasticity.

    Dietary intake of sulfur is primarily dependent on amino acids Methionine and Cysteine, but some people do not consume enough of these for their lifestyle. MSM was developed in 1982 under the brand OptiMSM and more recently was recognized as GRAS (generally recognized as safe) by the FDA.

    MSM (DMSO2) and DMSO both act as anti-inflammatory compounds through inhibition of inflammatory cytokines IL-6 and TNF-α. MSM may also reduce allergies if taken regularly. More recent studies indicate that regular MSM consumption may reduce wrinkles and restore skin elasticity.

    This product is 200 grams [7.05 oz] of pure MSM in a transparent, reclosable plastic jar with an integrated Safety Seal and Shrinkband.

    Also included are the certificate of analysis for the individual MSM batch and a 1.7cc measuring scoop which measures approximately 1000mg of MSM.

    More information on MSM can be found at

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Methylsulfonylmethane (MSM) Benefits and Uses


Commercially, MSM is taken as a dietary supplement for a variety of symptoms and conditions. The most popular uses today is for the management of joint and muscle pain and improvement of skin health and complexion. MSM is taken primarily for its perceived effect in reducing swelling and inflammation.




MSM is known by a number of alternative names including:

Dimethyl sulfone




Methyl sulfone

Crystalline dimethyl sulfoxide






Scientific Consensus:


MSM, as an oral supplement, may be effective in improving joint and muscle inflammation. MSM is taken primarily today for its perceived effect in reducing pain and swelling, specifically in joints and skin conditions. MSM is generally recognized as safe. Dosages of oral MSM used for therapeutic purposes are usually divided into three daily doses and range from 1,500 to 3,000 mg daily. 




All dietary supplements have risks. Please ensure that you are familiar with the latest research on effects, side effects, benefits, and uses of a supplement before buying it.


Store in a cool, dry place. Keep out of reach of children. If you have any underlying medical conditions or are taking any medication, please consult a medical professional before using this supplement. 


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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How We Research Our Content

Our content is written using meticulous research methods and claims are backed by links to scientific references, wherever possible. The author and editors of Liftmode's Research Team have strong academic backgrounds in microbiology, physiology, and biochemistry.

Content Updated On: September 10, 2020




  • Butawan, M., Benjamin, R. L., & Bloomer, R. J. (2017). Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients9(3), 290.

  • Liu X, Machado GC, Eyles JP, et al (2018) Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis British Journal of Sports Medicine; 52:167-175.