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Fisetin

Buy our Fisetin Supplement

 

Fisetin is a plant polyphenol compound similar to Quercetin, Rutin and Reservatrol. It is best known for its health-promoting, antioxidant, and anti-ageing benefits and can be extracted from a number of plant species. Fisetin has the chemical formula C15H10O6 and a molecular weight of 286,23 g/mol.

 

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What is Fisetin?

 

Fisetin (7,3′,4′-flavon-3-ol) is a flavonoid found in a variety of fruits and vegetables. Like other flavonoids, it is bright yellow and was even used in a dye called young fustic. Fisetin has a wide range of anti-inflammatory and antioxidant properties, though more recently it has gained attention as a potential senolytic and may promote healthy aging.

 

A senolytic is a compound that promotes death in older cells and can be thought of as “culling the herd” of animal cells. While this property is very poorly understood, Fisetin was able to extend the lifespan and reduce health complications in aging mice.

 

On top of its novel anti-aging properties, Fisetin has a wide range of other bioactivities that may be beneficial for a wide range of people. Fisetin has strong antioxidant and free-radical scavenging properties, which may promote healthy skin and brain health. Fisetin is a potent anti-inflammatory agent and directly inhibits the activity pro-inflammatory cytokines such as TNFα, NF-κB, and IL6.

 

This is not a surprise due to its structural relationship to the powerful anti-inflammatory Quercetin (Fisetin being 5-Deoxyquercetin), however Fisetin is believed to have nearly double the oral bioavailability and a wider range of effects. Flavonoids are often synergistic when taken in conjunction.

 

This product is Fisetin at ≥98% purity in a transparent, reclosable plastic jar with an integrated Safety Seal and Shrinkband.

Also included are the certificate of analysis for the individual Fisetin batch and a 0.625cc measuring scoop which measures approximately one serving of 250mg Fisetin.

 

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