Matrine is a naturally-occurring alkaloid found in Sophora flavescens. This herb is used in Traditional Chinese Medicine and is believed to enhance liver function. It has immune-modulating properties, and more recent studies indicate it is a potent anti-inflammatory. It also has unique mu and kappa opioid agonist properties that some users report synergize with herbs like kratom.
Matrine has been shown to reduce the expression of inflammatory mediators COX-2, TNF-α, IL-6 and ICAM-1, among other targets. It also may inhibit NF-κB. This combination of targets makes it a promising molecule for many types of inflammation. It also has potent ant-oxidant properties and inhibits neuronal apoptosis in mice following injury.
The oral bioavailability ranges from 17% to 44% depending on species. Sophora flavescens has other toxic molecules that make its use as a traditional medicine risky, however isolated Matrine shows much less toxicity than related molecules. However, at higher serving sizes, it may exhibit unpleasant psychotropic effects. Staying within the recommended dose range is highly recommended.
This product is 2 grams (0.07 oz) of pure Sophora flavescens extract, standardized to contain ≥98% Matrine in a transparent, reclosable jar with an integrated Safety Seal and Shrinkband.
Also included are the certificate of analysis for the individual Matrine batch and a 0.15cc measuring scoop. Three level scoops contain approximately one serving of 250mg Matrine. Use of a scale with 0.001g accuracy is recommended for reliable measurement.
More information on Matrine can be found at
https://en.wikipedia.org/wiki/Matrine
$29.68
