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Icariin

  • Helps to promote healthy sexual libido
  • Supports healthy testosterone levels
  • Supports a healthy metabolism

 

Icariin is a plant found primarily in China also known as Horny Goat Weed, and has a long history of use in traditional medicine for sexual health. Benefits include supporting a healthy libido, offering support to bones and cartilage, and supporting a healthy metabolism. LiftMode Icariin extracts are 90 or 98% pure, and come with a 1/32nd teaspoon measuring scoop (0.15cc), which contains approximately 50mg of Icariin. Recommended use is around 50-150 mg, depending on weight and desired strength.  

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Icariin supplement reviews

 

 “This product will give you a powerful rush of energy. A clean, crisp, mental sharpness than helps you concentrate. Highly recommended. And as always, shipping is very fast.” – John

 

“I got this product in order to boost my energy before workouts. For that purpose, it works extremely well! About 30 minutes to an hour after taking the icariin, I feel a definite surge of energy and I get much more into my workout than I do on a normal day. I also spar sometimes at my gym and I feel like I pack a lot more power in my punches after taking this.” - Chris

 

Icariin product reviews

 

  • Icariin is a plant found primarily in China also known as Horny Goat Weed and has a long history of use in traditional medicine for sexual health.

 

  • Benefits include treatment for ED, increased sexual libido, protection of bones and cartilage and lowering lipid levels in the blood.

 

What is Icariin?

 

Icariin or Horny Goat Weed extract is a natural flavonoid occurring in plants of the Epimedium genus, best known for supporting erectile health and a healthy libido. Icariin containing plants are found predominately in China and are woody, small and evergreen with characteristic flowers. Several studies have been done on Icariin, and the molecule has been found to have several beneficial actions which include supporting erectile function, providing antioxidant protection, and it may help ing lowering blood pressure, protecting against bone loss, and boosting testosterone.[1]

The use of plants from the Epimedium genus has a long history in China: there is over a thousand years of their recorded use for medical purposes, specifically male sexual health and treatment of kidney disorders.  In China, plants from the Epimedium genus have the name Yin Yang Hou, and are known more commonly as Fairy Wings or Horny Goat Weed because of their effects.  The plants enjoy deep shade, and are able to compete with tree roots making them good shade plants.[2] Traditionally, the leaves are used to create powdered extracts, but the plants also boast flowers of white, yellow and violet.

 

Icariin benefits/effects

 

The Icariin molecule is a flavonoid – a plant secondary metabolite – with the characteristic 15-carbon skeleton, two phenyl rings and a heterocyclic ring structure.  Icariin’s effects in the mammalian body include acting as a PDE5 inhibitor.[3] This allows continued function of cyclic GMP in the smooth muscles, allowing increased capillary blood flow to the penis and other smooth muscle areas (heart and lungs). Icariin’s best known effect, therefore, is its support of healthy erectile function[4]

Icariin extract has been shown to mimic the effects of testosterone in a recent study conducted by Zhen-Bao Zhang and Qing-Tao Yang at the Shantou University Medical College in China:

“(1) Icariin improved the condition of reproductive organs and increased the circulating levels of testosterone. (2) Icariin treatment also improved the steady-state serum BGP and might have promoted bone formation. At the same time, it decreased the serum levels of StrACP and might have reduced the bone resorption. (3) Icariin suppressed the extent of apoptosis of penile cavernosal smooth muscle cells.” (Yang and Zhang, 2006)[5]

A new study has shown that Icariin could potentially be used as a compound for cartilage tissue engineering[6] because it has been shown to up-regulate expression of genes responsible for chondroid tissue formation, and also to improve the restoration of osteochondral defects. This could allow Icariin to be used as an alternative to other growth factors, and indicates that it improves bone and cartilage tissue.

Icariin’s benefits also include protection against bone-loss.  A study has recently been published that confirms traditional Chinese use of the plant as a treatment for osteoporosis. It has been shown to produce anabolic effects in bone, which is of great importance to people with osteoporosis and other bone-tissue disorders.  This study shows further research by the same researchers who previously showed that icariin could increase bone mineral density and help to stimulate osteoblastic cell proliferation.[7]

Another use of icariin is to maintain healthy levels of lipids (fats) in the blood.  Hyperlipidemia is a disease which characteristically involves abnormally elevated levels of lipids (fats) in the blood, often caused by diabetes, and commonly found in people suffering from obesity.  Icariin has been shown to be beneficial for those with hyperlipidemia. The results of a recent study into Icariin’s effects:

indicate that icariin is a novel PPARα agonist, activates lipid metabolism gene expressions in liver, which could be a basis for its lipid-lowering effects and its beneficial effects against diabetes.”[8]

 

Icariin recommended use

 

A recent study by researchers at the US National Library of Medicine has found that for the best effects, Icariin dosage should be no higher than 10mg/ kg. [9]  This results in higher overall serum testosterone levels. When dosage is too high, the testosterone raising effects are diminished. However, at high doses the Icariin product can be used for nerve injury treatment. This would equate to around 900-1500mg, depending on body weight. 

Liftmode Icariin is 90-98% pure.  You can buy 5grams of 98% Icariin or buy 10 grams of 90% Icariin.  Other sellers of Icariin extracts include World Abs 60% pure product as well as GNC Icariin extract at 20% pure from Vitablast.

 

Icariin extract side effects / warnings

 

Icariin side effects have been researched thoroughly and it has been found that moderate use of Horny Goat Weed extracts very rarely results in negative side-effects. However, according to WebMD, it is possible to experience dizziness, dry mouth, thirstiness and vomiting if taken at high doses or for a long period of time. One man reported heart arrythmia after taking a product that stacked Icariin with other substances. It may be unsafe for pregnant women, people with bleeding disorders, low blood pressure or horome sensitive cancers. 

 

References

[1] “Comparative Effects of Er-Xian Decoction, Epimedium Herbs, and Icariin with Estrogen on Bone and Reproductive Tissue in Ovariectomized Rats”, Tiang Hang et al., Evidence-Based Complementary and Alternative Medicine,Volume 2012 (2012), Article ID 241416,

 

[2] An Evaluation Report on Barrenworts for the Shade Garden Mark R. Rudy, Plant Evaluator, Chicago Botanical Garden, Issue 20, 2003

 

[3] “Effects of icariin on phosphodiesterase-5 activity in vitro and cyclic guanosine monophosphate level in cavernous smooth muscle cells”, Ching-Shwun Lin et al., Journal of Urology, 2006

 

[4] “Effect of icariin on cyclic GMP levels and on the mRNA expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in penile cavernosum”, Benrong Hu et al., Journal of Huazhong University of Science and Technology, Vol 26, Issue 4, September 2006

 

[5] “The testosterone mimetic properties of icariin” Zhen-Bao Zhang and Qing-Tao Yang, Asian Journal of Andrology

Volume 8, Issue 5, pages 601–605, September 2006

 

[6] “Icariin: a potential promoting compound for cartilage tissue engineering”, Osteoarthritis Cartilage Reasearch Society,  Li D et al, Aug 2012

 

[7] “Icariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells”, Wen-Fang Chen et al, British Journal of Pharmocology, Vol 159 Issue 4,Feb 2010

[8] “Icariin Is A PPARα Activator Inducing Lipid Metabolic Gene Expression in Mice”, Feng Jin et al, Molecules Vol 19 Issue 11, November 2014

 

[9] “Erectogenic and Neurotrophic Effects of Icariin, a Purified Extract of Horny Goat Weed (Epimedium spp.) In Vitro and In Vivo “Lia Banie et al., NIH Manuscripts, Jan 2013. 

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