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Magnolia Bark Extract

  • Promotes better sleep
  • Supports healthy stress levels
  • Supports healthy cortisol levels
  • Stimulates glucocorticoid production


Magnolia bark is an ancient traditional remedy from Eastern medicine used for the treatment of stress and supporting a healthy mood. Magnolia bark extract contains mostly the biphenol neolignans Magnolol and Honokiol, which are effective in supporting healthy stress levels and healthy cortisol levels in the blood as well as stimulating natural glucocorticoid production. Magnolia bark extract is normally used at a dosage of 250-500 mg when it is very pure. Side effects of Magnolia bark extract taken in the proper amount are minimal, and there are many additional uses such as supporting fresh breath and lack of seizures.


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Magnolia bark supplement reviews


“LiftMode 95% Honokiol + Magnolol bark extract is great for beating the blues of every day life. larger dosages produce a sedative effect and produce a very tranquil sleep. The quality is superb and you cannot find this product anywhere else but at liftmode...” – Richard 


“I have bought this product several times and have been on it for 5 months... all I can testify is that it works, especially in combination with valerian root and 5-HTP. there's not a day that I don't use it... no side effects in my experience. a good choice for someone looking for a natural source. 9/10 rating effectiveness!” – OMAR 


Magnolia bark product reviews


  • Magnolia bark is an ancient traditional remedy from Eastern medicine used for reducing stress and to support a healthy mood


  • Magnolia bark extract contains mostly magnolol which is effective at supporting healthy stress levels and cortisol levels in the blood as well as stimulating natural steroids like gluccocorticoids.


  • Magnolia bark extract is normally used at around 300-500 mg when it is very pure




Magnolia bark (known as Houpu in Chinese medicine) is a well-known and well-used natural remedy for the reduction of stress and to support a healthy mood, as well as a treatment for over-eating due to stress. It has been used in Eastern medicine for thousands of years, and the first recorded use was in 100 A.D. by Shennong Jing:

“houpu is bitter and warm, non-toxic, mainly treating wind-stroke, cold damage, headache, cold and heat, fright qi, blood impediment, and dead muscle. It removes the three kinds of worms. It grows in mountains and valleys.”

The bark was a common ingredient in herbal recipes written around 220 A.D. by respected Chinese herbal practitioners, some of which are still used in traditional Chinese medicine today. Often the bark would be made in a formula which combined the use of other plants such as rhubarb, cinnamon, ginger and liquorice.[1] 


Magnolia bark benefits/effects


Two groups of chemicals, biphenols and essential oils, give Magnolia bark its characteristic smell, which was thought to awaken the spleen in ancient Chinese medicine. The biphenols are the main components of Magnolia bark which give it its pharmacological properties and these major chemicals are Magnolol and Honokiol.

Magnolia has been tested in several recent studies and has been shown to have a marked effect on mood and stress, and one of the major chemicals in the bark, Magnolol, has been found recently to stimulate steroidogenesis in mammalian adrenal cells.[2] One important group of steroids produced by the adrenal cells are the glucocorticoids, which have anti-asthmatic effects.[3] This is interesting because one of the indications for using Magnolia remedies in ancient Chinese medicine was for the treatment of asthma.

Magnolia officinalis, a Chinese medicinal herb, has long been used for the relief of fever, headache, stress, diarrhea, stroke, and asthma. Magnolol, one of the compounds isolated from Magnolia officinalis, acts on the central nervous system, inhibits platelet coagulation and lymphocyte proliferation, and is an anti-inflammatory agent and smooth muscle relaxant.”

One study showed that extracts of Magnolia in conjunction with a patented extract from Phellodendron amurense (a plant with similar biphenol compounds) could lower stress in both overweight men and women.  This double-blind placebo test study used 56 candidates who had been screen for moderate stress and anxiety symptoms, who were then treated with either the Magnolia, phellodendron combination (MP) or placebo.

These results indicate that daily supplementation with a combination of Magnolia bark extract and Phellodendron bark extract (Relora®) reduces cortisol exposure and perceived daily stress, while improving a variety of mood state parameters, including lower fatigue and higher vigor. These results suggest an effective natural approach to modulating the detrimental health effects of chronic stress in moderately stressed adults.”[4]

The same study showed the ability of Magnolia bark, in combination with other herbs, “to reduce both cortisol exposure and the perception of stress/anxiety, while improving weight loss in subjects with stress-related eating.”

There is also a synergetic relationship between Magnolol and ginger rhizome, which has been shown to produce strong anti-depressant effects.

Dr. Oz recommends using Magnolia bark for better sleep patterns.


Magnolia bark extract recommended use


According to the previously quoted article by Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, Portland, Oregon, entitled “Magnolia Bark”:

The usual dosage recommendation for Magnolia bark in decoction is 3-9 grams. It is also powdered in formulas made in pill form, in which case the daily dose ingested is typically less than 1 gram. Since prolonged boiling of the bark may reduce the content of essential oils and biphenols, the decoction requires a higher dose than the powder that is ingested in pills.”

LiftMode Magnolia bark extract is 95% pure biphenol neolignans, and can be bought in 50 gram or 20 gram containers. It comes with its own measuring spoon.


Magnolia bark extract side effects


One possible ‘side-effect’ use of Magnolia bark is for the reducing bad breath. In a recent study conducted with compressed-chewing gums containing Magnolia extracts, it was found that the two major components of Magnolia bark, Magnolol and Honokiol, were effective in killing bacteria responsible for bad-breath.

In conclusion, MBE demonstrated a significant antibacterial activity against organisms responsible for oral malodor and can be incorporated in compressed mints and chewing gum for improved breath-freshening benefits.[5]

An exciting use of Magnolia bark is in reducing the risk of suffering seizures and convulsions. In a recent study, it was found that Magnolia bark extract had a positive effect in the reduction of induced seizures and convulsions in rats, and has antiepileptic properties.[6]

Further studies have shown Magnolol to have anti-inflammatory and analgesic properties, as Eastern medicine has claimed for hundreds of years. Acetic-acid induced shock was depressed by Magnolol, indomethacin and ibuprofen. Unlike other anti-inflammatories, Magnolol does not increase the liver glycogen level, and has been shown to be less toxic than other modern synthetic analgesics.[7]




[1] "Magnolia Bark", Subhuti Dharmananda, March 2001

[2] "Effect of Magnolia officinalis and Phellodendron amurense (Relora®) on cortisol and psychological mood state in moderately stressed subjects", Shawn M Talbott, Julie A Talbott and Mike Pugh, Journal of the International Society of Sports Nutrition, 2013

[3] "Magnolol stimulates steroidogenesis in rat adrenal cells", Jian-Jung Chen et al., British Journal of Pharmacology, Nov 2000

[4] "Effect of Magnolia officinalis and Phellodendron amurense (Relora®) on cortisol and psychological mood state in moderately stressed subjects" Shawn M Talbott, Julie A Talbott and Mike Pugh, Journal of the International Society of Sports Nutrition 2013, 10:37

[5] "Compressed mints and chewing gum containing Magnolia bark extract are effective against bacteria responsible for oral malodour", Michael Greenberg, Philip Urnezis, Minmin Tian, Journal of Agricultural and Food Chemistry, 12/2007

[6] "Chinese herb constituent beta-eudesmol alleviated the electroshock seizures in mice and electrographic seizures in rat hippocampal slices." Chiou LC, Ling JY, Chang CC, Neuroscience Letters,  Aug 1997

[7] "Anti-inflammatory and analgesic effects of Magnolol", Chen-Chih Chen et al., Naunyn-Schmiedeberg's Archives of Pharmacology, Vol 366, Issue 6, Dec 1992