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Buy Our Oleamide Supplement


Oleamide (cis-9,10-octadecenoamide) is a derivative of oleic acid and is a functional fatty acid in the human brain. It is biosynthesized from oleic acid and ammonia and metabolized by FAAH. It has a molecular weight of 281.484 g/mol and the chemical formula C18H35NO.


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Oleamide reviews



Oleamide Benefits and Uses


Oleamide (also known as cis-9,10-octadecenoamide) is biosynthesized from oleic acid and ammonia in the human brain and the brains of most mammals. It is known to help regulate sleep patterns and to interact with the GABAergic system. It is also remarkably efficient at augmenting the signalling of the serotonergic system and is able to do so even at very low concentrations (as low as 1nM).


In mammals, it accumulates in the brain and nervous system during sleep deprivation. Anecdotally, it may have similar effects to other relaxing supplements. However, the significance of its benefits will only be fully understood once further research becomes available.


Where to Buy Oleamide Online?


LiftMode offers a variety of unit sizes of Oleamide, including a 50 gram (1.76 Oz) unit. Our Oleamide is guaranteed at an extremely high (98%) purity.

All our products ship with a certificate of analysis from 3rd-party independent laboratories, and all orders are covered by our 90-days refund/reshipment policy to ensure the highest quality.


Shipping restrictions: No shipping restrictions currently apply to this product and we are able to ship internationally. At checkout, the available shipping options for your location will be available.




Oleamide supplements are also known by a few different names, including:







Oleic acid amide


Oleyl Amide



Scientific Consensus:


Oleamide is a relatively new supplement and further research is required to fully understand the significance of its benefits, uses, and side effects. Using this supplement at the recommended serving size is likely safe for most adults.

DO NOT EXCEED THE RECOMMENDED SERVING SIZE. Use with caution. Do not use if pregnant or breastfeeding.


Warning: Oleamide may interact with a variety of medications. Please make sure that you speak to your doctor before using this supplement if you are taking any medication.



All dietary supplements have risks. Please ensure that you are familiar with the latest research on effects, side effects, benefits, and uses of a supplement before buying it.

Store in a cool, dry place. Keep out of reach of children. Do not exceed the recommended serving size. If you have any underlying medical conditions or are taking any medication, please consult a medical professional before using this supplement. 


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


buy oleamide supplment


How We Research Our Content

Our content is written using meticulous research methods and claims are backed by links to scientific references, wherever possible. The author and editors of Liftmode's Research Team have strong academic backgrounds in microbiology, physiology, and biochemistry.

Content Updated On: October 13, 2019




  • Mueller, G.P., Driscoll, W.J. (2009). Biosynthesis of oleamide. Vitam Horm. 81:55-78 

  • Basile, A.S., Hanus, L., Mendelson, W.B. (1999). Characterization of the hypnotic properties of oleamide. Neuroreport. 10(5):947-51. 

  • Coyne, L., Lees, G., Nicholson, R.A., Zheng, J., Neufield, K.D. (2002). The sleep hormone oleamide modulates inhibitory ionotropic receptors in mammalian CNS in vitro. British Journal of Pharmacology. 35(8):1977-1987.

  • Huidobro-Toro, J.P., Harris, R.A. (1996). Brain lipids that induce sleep are novel modulators of 5-hydroxytrypamine receptors. Proc Natl Acad Sci U S A. 23;93(15):8078-82.

  • Boger, D.L., Henriksen, S.J., Cravatt, B.F. (1998). Oleamide: an endogenous sleep-inducing lipid and prototypical member of a new class of biological signaling molecules. Curr Pharm Des. 4(4):303-14.