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(±)-Tetrahydroharmine (THH) Powder

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Unit Size: 0.25g
SKU: TE-TRAL-M250

Tetrahydroharmine (THH) is a compound found in the plant Banisteriopsis caapi, traditionally used in spiritual journeys by the indigenous shamans of South America as part of the plant infusion Ayahuasca.

Modern science has further investigated the unique nootropic, antioxidant, neuroprotective, neurogenesis-, cognition-, and mood-enhancing properties of THH.

Our (±)-Tetrahydroharmine contains both the (+) and (-) optical isomers. THH is known to mildly inhibit serotonin reuptake and may mildly interact with metabolic clearance of important neurotransmitters like dopamine and serotonin, which are involved in mood regulation and motivation.

Tetrahydroharmine is valued as a nootropic supplement to support cognitive clarity, mood balance, and stress management. It is also valued for its potential to promote calm focus and spiritual well-being.

These statements have not been evaluated by the Food and Drug Administration. This product is for use as a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease. Always consult a healthcare professional before starting any supplement regimen, especially if you are pregnant, breastfeeding, or have underlying health conditions. Avoid excessive consumption and do not exceed the recommended serving size.

Description

Tetrahydroharmine Benefits and Uses

Tetrahydroharmine (THH) is a compound found in the plant Banisteriopsis caapi –one of the key ingredients of Ayahuasca. Our Tetrahydroharmine is racemic (±)-Tetrahydroharmine, consisting of both the (+) and (-) optical isomers. It is known that Tetrahydroharmine is a mild serotonin reuptake inhibitor – and additionally, it is speculated that one isomer of our (±)-THH may weakly and reversibly inhibit the activity of an enzyme called monoamine oxidase A (MAO-A), which regulates the functioning of important monoamine neurotransmitters – including dopamine and serotonin. Dopamine and serotonin play important roles in regulating motivation, perception, and overall mood. The net effect of increasing these chemical messengers is said to be an overall improvement in mood, cognitive clarity, and an increased sense of calm focus.

THH can be used as a nootropic and neuroprotective compound that may offer additional beneficial effects, including stress relief and mood improvement. A scientific study published in the renowned journal Nature has also recently uncovered a very unique property of THH and related harmala alkaloids in enabling adult neurogenesis. THH is also used synergistically with other MAO substrate ingredients that have cognitive-enhancing and mood-enhancing effects, including natural indole and phenylethylamine derivatives.

Tetrahydroharmine is known by a number of alternative names, including:

  • (±)-Tetrahydroharmine
  • THH

Scientific Consensus

Tetrahydroharmine (THH) is a compound that may modulate key neurotransmitters, such as dopamine and serotonin. It is taken primarily for its nootropic, neuroprotective, and neurogenesis-promoting effects, as well as its ability to improve mood and cognitive function and reduce feelings of stress.

Further clinical research is required to support the safety, optimal serving size, and potential benefits of THH more fully

Caution: Please consult your doctor before using Tetrahydroharmine (THH).

These statements have not been evaluated by the Food and Drug Administration. This product is for use as a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease. Always consult a healthcare professional before starting any supplement regimen, especially if you are pregnant, breastfeeding, or have underlying health conditions. Avoid excessive consumption and do not exceed the recommended serving size.

Instructions & Ingredients

As a Nootropic Compound, take 1 serving up to 2 times per day. Please start with the lowest suggested single serving quantity to assess response.

Supplement Facts
Serving size: 50mg Servings per container: 5
Amount per serving % DV
(±)-Tetrahydroharmine (THH) 50 mg
‡ Daily Value not established.

Where To Buy

LiftMode offers a variety of unit sizes of HPLC-tested (±)-Tetrahydroharmine (THH) Powder, including a 0.25g unit, a 0.5g unit, a 5g unit and a 2g unit. Our (±)-Tetrahydroharmine (THH) Powder is of the highest quality.

Disclaimer & Other Info

Store securely in a dry cool location away from direct sunlight. Keep out of reach of children and pets. Do not take this or any other supplement, and instead consult doctor about use, if you are under the age of 18, pregnant or breastfeeding, taking prescription or OTC / nonprescription drugs, or if you have any known or suspected medical conditions. Do not use if the product safety seal was damaged or missing upon receipt.

The statements on this page have not been evaluated by the FDA. The products on this page are not intended to diagnose, treat, cure, or prevent any disease.

Tetrahydroharmine (THH) Powder 2 grams.
Regular price $13.68
Regular price $18.68 Sale price $13.68
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  • Tetrahydroharmine (THH)
Tetrahydroharmine (THH)
Tetrahydroharmine (THH)

Tetrahydroharmine (THH)

Tetrahydroharmine (THH) is one of a family of β-carboline (indole-related) harmala alkaloids, found in the Banisteriopsis caapi (yagé, or ayahuasca) vine and related species, as well as in Peganum harmala (which lends these alkaloids their "harmala alkaloid" nomenclature). Scientific research has revealed that (±)-Tetrahydroharmine functions as a mild serotonin reuptake inhibitor, and one isomer may also have gentle weak reversible MAOI activity (much less potent than that of Harmaline or Harmine), allowing for synergies with other natural phytochemicals that may be deactivated by MAO, including indole derivatives. In addition, THH has nootropic potential. Studies suggest that the neuroprotective β-carboline harmala alkaloids from the Banisteriopsis caapi vine, including THH, uniquely promote adult neurogenesis. The combination of bioactivities in THH may help support healthy serotonin levels and promote a positive and open mood. - Supports Healthy Mood - Helps Manage Stress - Powerful Neuroprotective

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References

National Center for Biotechnology Information. PubChem Database(2020). Tetrahydroharmine. Retrieved June, 2020, https://pubchem.ncbi.nlm.nih.gov/compound/Tetrahydroharmine.

Frecska, E., Bokor, P., & Winkelman, M. (2016). The Therapeutic Potentials of Ayahuasca: Possible Effects against Various Diseases of Civilization. Frontiers in pharmacology, 7, 35.

Callaway JC, McKenna DJ, Grob CS, et al. Pharmacokinetics of Hoasca alkaloids in healthy humans. J Ethnopharmacol. 1999;65(3):243-256. doi:10.1016/s0378-8741(98)00168-8