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Kanna Extract

Buy Our Kanna Extract Supplement


Kanna Extract is a powerful mood-support supplement derived from the African succulent, Sceletium tortusum. It grows naturally in the Namaqualand region of South Africa and has been used for millennia by the Khoisan bushmen. Our extract contains very high concentrations of the alkaloids Mesembrine and Mesembrenone.


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Kanna Extract Reviews


Kanna Extract Benefits and Uses


Anecdotally, Kanna extracts are said to produce tranquil yet improved states of mood, while acting as a mild stress-reducing supplement. Some people use Kanna extract for cognition. Research has indicated that Kanna extract acts as a mild SRI (serotonin reuptake inhibitor) and an inhibitor of the PDE4 enzyme.


Kanna extract contains several important alkaloids. For purposes of taxonomy, scientists have given all of the Kanna-derived alkaloids the prefix: “mesembr-”. The most important alkaloids include:


  1. Mesembrine: A powerful serotonin reuptake inhibitor.

  2. Mesembrenone: Inhibits both serotonin reuptake and the activities of PDE-4 enzymes.

  3. Mesembrenol: Secondary alkaloid with similar effects.

  4. Mesembranol: Secondary alkaloid with similar effects.

Where to Buy Kanna Extract Online?


LiftMode offers a variety of unit sizes of Kanna Extract, including a 1-gram sample, a 2-gram (0.07 Oz) unit and a 5-gram (0.18 Oz) unit. Our Kanna Extract is standardized to >5% alkaloids, with a minimum of >3% Mesembrine.

All our products ship with a certificate of analysis from 3rd-party independent laboratories and all orders are covered by our 90-days refund/reshipment policy to ensure the highest quality.


Shipping restrictions: No shipping restrictions currently apply to this product and we are able to ship internationally. At checkout, the available shipping options for your location will be available.  




Kanna Extract is known by a number of alternative names, including:


Sceletium Tortuosum










Scientific Consensus:


An extremely long history of use suggests that using the fermented plant is safe and effective, but does not provide sufficient proof. Further, very few studies have been conducted using a strong Kanna Extract. More research is needed to fully understand the significance of the benefits and adverse effects of this supplement.


There is not enough research about the safety of Kanna Extract for pregnant and breastfeeding women.  




All dietary supplements have risks. Please ensure that you are familiar with the latest research on effects, side effects, benefits, and uses of a supplement before buying it.


Store in a cool, dry place. Keep out of reach of children. If you have any underlying medical conditions or are taking any medication, please consult a medical professional before using this supplement. 


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


buy kanna extract supplement


How We Research Our Content

Our content is written using meticulous research methods and claims are backed by links to scientific references, wherever possible. The author and editors of Liftmode's Research Team have strong academic backgrounds in microbiology, physiology, and biochemistry.

Medically Reviewed by: Dr. Karen Vieira, PhD in Biomedical Sciences

Content Updated On: October 16, 2019




  • Terburg, D., Syal, S., Rosenburger, L. A., Heany, S., Philips, N., Gericke, N., Stein, D. J., & van Honk, J. (2013). Acute effects of Sceletium tortuosum (Zembrin), a dual 5-HT reuptake and PDE4 inhibitor, in the human amygdala and its connection to the hypothalamus. Neuropsychopharmacology. 38(13):2708-16.


  • Harvey, A. L., Young. L. C., Viljoen, A. M., & Gericke. N.  P. (2011). Pharmacological actions of the South African medicinal and functional food plant Sceletium tortuosum and its principal alkaloids. J Ethnopharmacol. 137(3):1124-9.


  • Chiu, S., Gericke, N., Farina-Woodbury, M., Badmaev, N., Raheb, H... Goble, L. (2014). Proof-of-concept randomized controlled study of cognition effects of the proprietary extract Sceletium tortuosum (Zembrin) targeting phosphodiesterase-4 in cognitively healthy subjects: Implications for Alzheimer’s dementia. Evid Based Complement Alternat Med. 2014:682014.


  • Smith, M. T., Crouch, N. R., Gericke, N., & Hirst, M. (1996). Psychoactive constituents of the genus Sceletium N.E.Br. and other Mesembryanthemaceae: a review. J Ethnopharmacol. 50:119-30.


  • Patnala, S., & Kanfer, I. (2009). Investigations of the phytochemical content of Sceletium tortuosum following the preparation of “Kougoed” by fermentation of plant material. J Ethnopharmacol. 121:86-91