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Buy Our Synephrine Supplement


Synephrine HCl (P-hydroxy-α-{methylaminomethyl}benzylalcohol, P-Synephrine, para-Synephrine) is a trace amine found in some species of plants, including the Bitter orange. It has the chemical formula C9H13NO2 and a molar mass of 167.21 g/mol.


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Synephrine Reviews



Synephrine Benefits and Uses


Synephrine HCl is often taken for thermogenic effects. Anecdotally, Synephrine may have similar effects to other energizing supplements, with short-lived but intense effects.


Where to Synephrine Online?


LiftMode offers a variety of unit sizes of Synephrine, including a 5-gram sample, a 20-gram (0.71 Oz) unit, and a 50-gram (1.76 Oz) unit. Our Synephrine is of the highest quality and is guaranteed at 98+% purity.

All our products ship with a certificate of analysis from 3rd-party independent laboratories, and all orders are covered by our 90-days refund/reshipment policy to ensure the highest quality.


Shipping restrictions: No shipping restrictions currently apply to this product and we are able to ship internationally. At checkout, the available shipping options for your location will be available.




Phenylethylamine is known by a number of alternative names including:


Synéphrine HCl

Synephrine Hydrochloride




Bitter orange extract (for naturally-derived Synephrine)


Scientific Consensus:


Synephrine is a compound that is produced in several plant species and can also be manufactured in a laboratory. Further research is necessary to fully understand the significance of its effects and adverse effects. It may increase heart rate and blood pressure, and may cause agitation.


DO NOT EXCEED THE RECOMMENDED SERVING SIZE. Use with caution. Do not use if pregnant or breastfeeding.




All dietary supplements have risks. Please ensure that you are familiar with the latest research on effects, side effects, benefits, and uses of a supplement before buying it.


Store in a cool, dry place. Keep out of reach of children. If you have any underlying medical conditions or are taking any medication, please consult a medical professional before using this supplement. 


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


buy synephrine supplement


How We Research Our Content

Our content is written using meticulous research methods and claims are backed by links to scientific references, wherever possible. The author and editors of Liftmode's Research Team have strong academic backgrounds in microbiology, physiology, and biochemistry.

Content Updated On: October 18, 2019




  • Stohs, S. J., Preuss, H. G., Keith, S. C., Keith, P. L., Miller, H., & Kaats, G. R. (2011). Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. International journal of medical sciences, 8(4), 295–301. doi:10.7150/ijms.8.295

  • Kaats, Gilbert & Leckie, Robert & Mrvichin, Nate & Stohs, Sidney. (2017). “Increased eating control and energy levels associated with consumption of bitter orange (p-synephrine) extract: a randomized placebo-controlled study.” Nutrition and Dietary Supplements. 9, 29-35. 10.2147/NDS.S136756.

  • Haaz, S., Fontaine, K. R., Cutte, G., Limdi, N., Perumean-Chaney, S., & Allison, D. B. (2006) Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update. Obes Rev. 7(1):79-88.

  • Suzuki, O., Matsumoto, T., Oya, M., & Katsumata, Y. (1979). Oxidation of synephrine by type A and type B monoamine oxidase. Experientia. 15;35(10):1283-4.

  • Stohs, S. J., Preuss, H. G., Shara, M. (2012). A Review of the Human Clinical Studies Involving Citrus aurantium (Bitter Orange) Extract and its Primary Protoalkaloid p-Synephrine. International Journal of Medical Sciences. 9(7):527-538.